Please put a moratorium on these cutesy names for special edition DVD releases, because it's gotten ridiculous. When they're short, they're more palatable (such as the Clueless "Whatever" edition), But when you start using entire quotes, it begins to be ungainly.
Worse, it might just reek of desperation. Although I know Planes, Trains and Automobiles has lots of fans (I don't happen to be one of them), could the use of the most famous quote be a way to remind people of what movie this is? Hey you thirtysomethings out there: Remember that scene with John Candy and Steve Martin in bed together? Yeah, it's from this movie right here, so don't forget to buy the right one!
And on one final note: It's my considered opinion that Edie McClurg gets the best line in the movie. But as short and concise as it is, It probably wasn't a likely contender for the name of this edition.